Im haloperidol in pregnancy

Haloperidol use may lead to the development of symptoms that resemble Parkinson's disease, but that are not caused by Parkinson's. These symptoms may include a taut or mask-like expression on the face, drooling, tremors, pill-rolling motions in the hands, cogwheel rigidity (abnormal rigidity in muscles, characterized by jerky movements when the muscle is passively stretched), and a shuffling gait. Taking the anti-Parkinson drugs benztropine mesylate or trihexyphenidyl hydrochloride along with haloperidol help to control these symptoms. Medication to control Parkinsonian-like symptoms may have to be continued after haloperidol is stopped. This is due to different rates of elimination of these drugs from the body.

CNS depression potentiated with alcohol, other CNS depressants. Possible neurotoxicity with lithium: monitor, discontinue if occurs. Caution with drugs that prolong the QT interval (eg, ketoconazole, paroxetine). May be potentiated by CYP3A4 inhibitors/substrates or CYP2D6 enzymes (eg, itraconazole, nefazodone, buspirone, venlafaxine, alprazolam, fluvoxamine, quinidine, fluoxetine, sertraline, chlorpromazine, promethazine. May be antagonized by CYP3A4 inducers (eg, rifampin, carbamazepine); monitor and adjust doses. May increase intraocular pressure with anticholinergics. Monitor anticoagulants.

The intravenous route is not FDA approved and is generally not recommended except when no other alternatives are available. Intravenous administration appears to be associated with a higher risk of QT prolongation and torsade de pointes (TdP) than other forms of administration. The manufacturer recommends ECG monitoring for QT prolongation and arrhythmias if IV administration is required. A dose in the range of 1 to 5 mg IV has been suggested, with the dose being repeated at 30 to 60 minute intervals, if needed. A maximum IV dose has not been established. The lowest effective dose should be used in conjunction with conversion to oral therapy as soon as possible.

processing.... Drugs & Diseases haloperidol (Rx) Brand and Other Names: Haldol, Haldol Decanoate, more... Haloperidol LA, Peridol

  • Classes: Antipsychotics, 1st Generation
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Sections haloperidol (Rx)
  • Sections haloperidol
  • Dosing & Uses
  • Interactions
  • Adverse Effects
  • Warnings
  • Pregnancy
  • Pharmacology
  • Administration
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Dosing & Uses Adult Pediatric Geriatric Dosage Forms & Strengths tablet

3 to 12 years and 15 to 40 kg :
-Initial dose: mg/day orally in 2 to 3 divided doses
-Maintenance dose: to mg/kg/day

Comments :
-The daily dose may be increased every 5 to 7 days in mg increments.
-There is little evidence that behavior improvement is further enhanced by doses greater than 6 mg/day.
-Limitation of use: Treatment should be reserved for patients with severe behavior problems and/or hyperactive children only after failure to respond to psychotherapy or medications (other than antipsychotics).

Uses :
-Treatment of severe behavior problems in children, including combative, explosive hyperexcitability not accounted for by immediate provocation
-Short-term treatment of hyperactive children with excessive motor activity and accompanying conduct disorder with impulsivity, difficulty sustaining attention, aggressiveness, mood lability, and/or poor frustration tolerance.

Im haloperidol in pregnancy

im haloperidol in pregnancy

processing.... Drugs & Diseases haloperidol (Rx) Brand and Other Names: Haldol, Haldol Decanoate, more... Haloperidol LA, Peridol

  • Classes: Antipsychotics, 1st Generation
  • Share
  • Email
  • Print
  • Feedback
Close
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
Sections haloperidol (Rx)
  • Sections haloperidol
  • Dosing & Uses
  • Interactions
  • Adverse Effects
  • Warnings
  • Pregnancy
  • Pharmacology
  • Administration
  • Images
  • Patient Handout
  • Formulary
Dosing & Uses Adult Pediatric Geriatric Dosage Forms & Strengths tablet

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