Hypogonadism in a male refers to a decrease in either of the two major functions of the testes: sperm production or testosterone production. These abnormalities can result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism). The use of testosterone to treat hypogonadism in adult men, primary or secondary, is reviewed here. The clinical manifestations and diagnosis of male hypogonadism, induction of spermatogenesis in men with secondary hypogonadism, and induction of puberty with testosterone are discussed elsewhere. (See "Clinical features and diagnosis of male hypogonadism" and "Induction of fertility in men with secondary hypogonadism" and "Diagnosis and treatment of delayed puberty", section on 'Testosterone therapy' .)
Also known as “velvet bean”, Mucuna pruriens is a tropical plant that is known for its ability to reduce the level of prolactin (a female hormone) in the bloodstream. As the male body contains both male and female hormones, Mucuna pruriens lowers prolactin levels in men, which helps to prevent testosterone depletion. Another important benefit of Mucuna pruriens is its ability to lower the level of cortisol (. the “stress hormone”) in the bloodstream. Clinical research shows that cortisol essentially dismantles testosterone molecules before they are even able to leave the testes.