How do you protect yourself against this? Well, when taking Deca Durabolin you can also take ant-estrogen medications to counter the results. Things like Nolvadex and Arimidex are popular choices. Both approach limiting the effects of estrogen different and will have different side effects on your health worth considering. Even with side effects though it is still worth pursuing either of these options. Gynecomastia is a particularly big problem due to how the imbalance between estrogen and progesterone is what leads to gynecomastia. So, by keeping your hormone levels regulated, you reduce the risk of potential unwanted growth.