Nandrolone decanoate is a nandrolone ester , or a prodrug of nandrolone .     As such, it is an androgen and anabolic steroid , or an agonist of the AR, the biological target of androgens like testosterone and DHT.     Relative to testosterone, nandrolone decanoate has enhanced anabolic effects and reduced androgenic effects.    It is considered to have strong anabolic effects but weak androgenic effects, with respective potency ratios of – and – (index value – or about an 11:1 ratio of myotrophic to androgenic effect) relative to testosterone propionate .    Along with oxandrolone (which has a ratio of about 10:1), nandrolone esters are thought to have the highest ratio of anabolic to androgenic effect of any other AAS.   For this reason, they are considered to be among the most appropriate AAS for use in women. 
Using a randomized "double-blind" "placebo-controlled" design, 16 experienced male bodybuilders (age: 19-44 yr) either received ND (200 (-1), intramuscularly) or placebo for 8 wk. Body composition was assessed using the four-component model, combining results from underwater weighing, dual-energy x-ray absorptiometry (DXA), and deuterium dilution. Total bone mineral content and density were measured using DXA. Water compartments (extracellular water [ECW] and intracellular water [ICW]) were determined using deuterium dilution and bromide dilution.
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