I’m sure that some people who read this will become angry, as there no doubt are some people who will read this who sell thyroid support supplements and thyroid boosters. Once again, I’m not suggesting that all of these products are junk, but just that you need to be cautious when purchasing ANY type of supplements. And in no way am I trying to promote any specific type of supplement, because while I definitely have a preference as to what supplements I recommend to my patients, there of course are a number of good companies out there.
I’m writing for my 80-year old neighbor. She does not have a computer. She has horrible knee pain from years of working in factories on concrete floors (she says that what it’s from). She has also been taking a blood thinner for about 20 years because of a TIA. She has been taking a Norco-type pain reliever that she does not want to take anymore mostly because it doesn’t work. She is desperate to find something that will relieve the pain. She can hardly bend her legs and has constant pain, even at night. Can a person on blood thinners take this Heal ‘n Soothe? I would even buy it for her myself if she can. She can’t take any OTC pain relievers because of the blood thinner she takes. Thank you for your help.
The effect of a nutritional source of tryptophan on dieting-induced
changes in brain 5-HT function.
Psychol Med. 2003.
Dieting in healthy women results in a decrease in the availability of tryptophan, the amino-acid precursor of serotonin, for brain serotonin synthesis. This is associated with increases in the prolactin response to serotonin drug challenge suggesting a 'supersensitivity' of serotonin neuroendocrine responses. The aim of the study was to assess whether increased tryptophan intake during dieting would prevent the changes in tryptophan availability and serotonin neuroendocrine function. Fifty female subjects underwent a 1000 kcal daily diet for 3 weeks. In the final week of the diet subjects were randomly allocated to receive either nutritionally-sourced tryptophan ( g daily) or placebo in a double-blind, parallel group, design. Tryptophan supplementation failed to modify the dieting-induced reduction in fasting tryptophan availability to the brain. However, in contrast to placebo-treated subjects, subjects receiving additional tryptophan did not show enhanced prolactin responses to intravenous tryptophan challenge. The decrease in tryptophan availability produced by dieting may be due to increased tryptophan metabolism rather than decreased tryptophan intake. While tryptophan treatment did not increase fasting tryptophan availability it may have modified the effect of dieting on brain serotonin function. Further studies will test the effect of tryptophan has consequences for the effectiveness of dieting as means of weight control.