Side effects of equioxx

Josh R Donnell, David D Frisbie

Department of Clinical Sciences, Orthopedic Research Center, Colorado State University, Fort Collins, CO, USA

Abstract: This review presents the pathogenesis and medical treatment of equine osteoarthritis (OA), focusing on firocoxib. Inhibition of prostaglandin E2 remains a fundamental treatment for decreasing clinical symptoms (ie, pain and lameness) associated with OA in horses. Nonsteroidal anti-inflammatory drugs (NSAIDs), which inhibit the production of prostaglandin E 2 from the arachidonic acid pathway, continue to be a mainstay for the clinical treatment of OA. Firocoxib is a cyclooxygenase (COX)-2-preferential NSAID that has been shown to be safe and to have a 70% oral bioavailability in the horse. Three clinical reports identified symptom-modifying effects (reduction in pain and/or lameness) in horses with OA administered the once-daily recommended dose ( mg/kg) of oral firocoxib following 7 days of administration. Other reports have suggested that a one-time loading dose ( mg/kg) of firocoxib provides an earlier (1–3 days) onset of action compared to the recommended dose. It is noteworthy that OA disease-modifying effects have been reported in horses for other COX-2-preferential NSAIDs (meloxicam and carprofen), but have not been attributed to firocoxib due to a lack of investigation to date.

Keywords: horse, osteoarthritis, firocoxib, COX-2 inhibitor, NSAID

6.) Quality Joint Supplements :    We shouldn’t forget about oral joint supplements like glucosamine chondroitin or hyaluronic acid when it comes to chronic inflammatory issues like osteoarthritis. One study showed glucosamine chondroitin to be to be successful in treating degenerative joint disease while Dr. Eleanor Kellon has held field trials and found certain formulas of both glucosamine chondroitin and HA to be effective in treating equine osteoarthritis (as documented in her book, Horse Journal: Guide to Equine Supplements and Nutraceuticals ). The tricky part about joint supplements, however, is finding a quality supplement with a high enough dosing. Dr. Kellon’s book mentions several good options, one being Corta-Flx .

                We can start to understand that frequent small meals are required in order to keep the stomach from being empty and causing a less damaging effect on the horses stomach. Such feedings of roughage, the amount and types can also play a role in preventing the increase of stomach acid. The horse’s chewing produces more saliva and by the horse swallowing the saliva helps neutralize stomach acid. Also certain types of medications that may increase the risk of ulcers may be those containing NSAIDS anti-inflammatory or any other medication that may block the production of prostaglandin E2 also known as PgE2 which is a chemical that decreases the acid production therefore when there is a low amount of PgE2 levels in the stomach there is a higher level of acid which lead to ulcers developing.

The same type of radiation used to treat cancer has been shown to "quiet " the inflammation and pain associated with arthritis in pets and humans when given in low doses. But you have to travel far from my home in South Texas to find this option. Although veterinarians in the United States rarely if ever suggest radiotherapy to combat arthritic problems in pets, it is commonly used for that purpose in dogs in Europe.  At the doses that are generally administered, many veterinarians there feel that its benefits outweigh its possible risks. In Europe, radiation treatment for human arthritis is an older accepted therapy as well ( ref 1 ) ( r e f 2 ) ( ref 3 ) , and it has been used in pets on that continent since at least the 1970s ( ref ) . Recent experimental studies in rodents confirm that these beneficial effects of radiation on swelling, pain and inflammation are real. ( ref )  Facilities I know of that offer this therapy include the Tierspital in Zurich   ( Dr. Bley ) and the Veterinary Oncology Center in Bologna ( ref ) .

Side effects of equioxx

side effects of equioxx

The same type of radiation used to treat cancer has been shown to "quiet " the inflammation and pain associated with arthritis in pets and humans when given in low doses. But you have to travel far from my home in South Texas to find this option. Although veterinarians in the United States rarely if ever suggest radiotherapy to combat arthritic problems in pets, it is commonly used for that purpose in dogs in Europe.  At the doses that are generally administered, many veterinarians there feel that its benefits outweigh its possible risks. In Europe, radiation treatment for human arthritis is an older accepted therapy as well ( ref 1 ) ( r e f 2 ) ( ref 3 ) , and it has been used in pets on that continent since at least the 1970s ( ref ) . Recent experimental studies in rodents confirm that these beneficial effects of radiation on swelling, pain and inflammation are real. ( ref )  Facilities I know of that offer this therapy include the Tierspital in Zurich   ( Dr. Bley ) and the Veterinary Oncology Center in Bologna ( ref ) .

Media:

side effects of equioxx

http://buy-steroids.org