Side effects of low testosterone treatment

And, exacerbating these two age-related erosive events, some catabolites of tryptophan can lead to the formation of mutagenic nitrosamines or the activation of an immunosuppressive receptor (which is usually triggered by toxicants such as xenobiotics), promoting carcinogenesis (Mezrich, et al., 2010; Chung & Gadupudi, 2011).

The consumption of a supplement of tryptophan will likely nurture or augment these disastrous age-associated disease states, by raising injurious tryptophan derivatives (particularly in the presence of a vitamin B6 deficiency, an insufficiency of stomach acid, a magnesium deficit, and a vitamin B3 deficiency).

Furthermore, tryptophan side effects in regards to greater mortality were shown in animal experiments (., Catrina, et al., 2001) using melatonin, whereas the study authors cautioned:

“[...] melatonin had a deleterious effect on the survival rate raising the question whether it is correct to assume that the hormone shows lack of adverse reactions.” [emphasis added]

In regard to serotonin's involvement in the promotion of higher mortality, one of its anti-longevity effects is conceivably the reabsorption of phosphate (a pro-inflammatory chemical) by the kidneys since klotho, an anti-aging protein, facilitates the excretion of phosphate from the kidneys (Peat, Nov. 2012).

Since tryptophan, serotonin, and melatonin meddle with basic energy production in cells, and since metabolic efficiency and functionality decreases proportionally with aging (Fannin, et al., 1999; O'Toole, et al., 2010) due to various factors, it seems coherent in biological terms that these substances are less prevalent, thus less “essential” or needed, in older people, as a further decrease of an already suboptimal general metabolic working order will aggravate physiological function systematically, increase the risk for disease (as exemplified and foreshadowed with tryptophan side effects), promote the aging process, and explains the increased mortality related to the administration of these substances.

Several tryptophan side effects, such as tryptophan's carcinogenic activities, the deterioration of metabolic energy function, and the promotion of hypertension, can rather readily account for a greater death rate.

Hello I hear this a lot about people saying magnesium gives them stomach distress there different types of magnesium 95% of the magnesium out there does go straight out your bowels the one magnesium that you need to get is called magnesium GLYniate doctors best Has a great magnesium GLY that is 100% absorbable And the beauty of it it gets into your cells which is where it’s needed instead of out through the toilet when it’s not wanted. We learned this from a natural path my daughter take 600 mg before bed I take 800 mg before bed it does not give us any diarrhea whatsoever in fact it has helped her migraines and my fibromyalgia immensely

Spironolactone is frequently used as a component of hormone replacement therapy in transgender women , especially in the United States (where cyproterone acetate is not available), usually in addition to an estrogen . [50] [51] [52] Spironolactone significantly depresses plasma testosterone levels, reducing them to female/castrate levels at sufficient doses and in combination with estrogen. The clinical response consists of, among other effects, decreased male pattern body hair , the induction of breast development , feminization in general, and lack of spontaneous erections . [52]

Side effects of low testosterone treatment

side effects of low testosterone treatment

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