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A study by the Department of Orthopedics at Red Cross Hospital in China found that boron supplements can increase bone formation and inhibit bone resorption, producing therapeutical protection against osteoporosis in animal studies. When rats were fed a boron-deprived diet, they experienced spongy bones, bone loss in the femurs and lumbar vertebrae, and increased osteoporotic conditions. On the other hand, rats given high-boron supplements showed improvements in bone mass, bone thickness, bone volume and higher levels of estradiol (a hormone tied to bone health). ( 6 )