As a long acting injection, zuclopenthixol decanoate comes in a 200 mg ampoule. Doses can vary from 50 mg 3 weekly to (rarely) 400 mg 2 weekly. In general, the lowest effective dose to prevent relapse is preferred. The interval may be shorter as a patient starts on the medication before extending to 3 weekly intervals subsequently. The dose should be reviewed and reduced in side effects occur, though in the short term an anticholinergic medication benztropine may be helpful for tremor and stiffness, while diazepam may be helpful for akathisia. 100 mg of zuclopenthixol decanoate is roughly equivalent to 20 mg of flupentixol decanoate or mg of fluphenazine decanoate.
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